Open CRISPR 1: World’s first open-source AI scissor edits human genes.
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 Published On Apr 27, 2024

Profluent has announced that it makes the OpenCRISPR-1 technology freely available through open-sourcing. This move allows individuals, academic institutions, and companies to explore and experiment with the technology at no cost.

While it’s customary for AI researchers to open source the software powering their AI systems to foster collaboration and innovation, it’s less common for biological labs and pharmaceutical companies to take a similar approach with inventions like OpenCRISPR-1.

It’s worth noting that while Profluent is sharing the gene editors produced by its AI technology, it is not releasing the underlying AI technology itself to the public domain.

The technology operates on a model that draws insights from sequences of amino acids and nucleic acids. These chemical compounds form the basis of the microscopic biological mechanisms scientists use in gene editing.

In essence, the system scrutinizes the functions of CRISPR gene editors found in nature, learning from them to create entirely novel gene editors.

“These A.I. models learn from sequences — whether those are sequences of characters or words or computer code or amino acids,” Profluent CEO Ali Madani stated to The New York Times.

The gene editors developed by Profluent are built upon the pioneering techniques recognized with Nobel Prizes, which revolve around biological mechanisms known as CRISPR.

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