The BBVA Foundation Frontiers of Knowledge Award in Biology and Biomedicine has gone in this sixteenth edition to the four scientists who unraveled the physiological mechanisms behind protein function, a fundamental finding to elucidate the origin of multiple diseases and develop new therapeutic strategies. Firstly, professors Ulrich Hartl (Max Planck Institute of Biochemistry, Germany) and Arthur Horwich (Yale University, United States) identified the cellular machinery that drives protein folding, a key process enabling them to fulfill their biological function; and subsequently, Kazutoshi Mori (Kyoto University, Japan) and Peter Walter (Altos Labs and University of California, San Francisco) discovered the response mechanism that targets wrongly folded proteins for repair or degradation.

Discover more here: https://www.frontiersofknowledgeaward...

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