CDC, Friday 18th June, Review potential link between heart inflammation and mRNA vaccines

https://www.medscape.com/viewarticle/...

https://www.cdc.gov/vaccines/acip/mee...

COVID-19 mRNA vaccines in adolescents and young adults: benefit-risk discussion
Discussion

CDC’s Advisory Committee on Immunization Practices

CDC, identified 216 cases of heart inflammation after 1st dose

Another 573 cases after the second shot

172 million people, at least one shot (789)

One in 217, 997

https://www.fda.gov/media/150054/down...

Under 30 years, n = 475

285 with known disposition

15 still in hospital

3 ICU

270 discharged

180 (81%) full recovery

41 (19%) ongoing signs or unknown status

Myocarditis in over 12s

Presence of one, new or worsening

Chest pain pressure discomfort

Dyspnea SOB pain with breathing

Palpitations

ECG changes

Troponins

Abnormal cardiac function

Pericarditis

Acute chest pain

Pericardial rub

New ST elevation or PR depression

New or worsening pericardial effusion

CDC safety expert Tom Shimabukuro

We’re still learning about the rates of myocarditis and pericarditis

As we gather more information we’ll begin to get a better idea of the post-vaccination rates

and hopefully be able to get more detailed information by age group

Mr Biden

https://www.bbc.co.uk/news/uk-57436535

Confirmed 500 million doses of Pfizer

92 low and middle-income countries and the African Union

Manufactured from August

Mr Biden

The United States is providing these half billion doses with no strings attached.

Our vaccine donations don't include pressure for favours, or potential concessions.

We're doing this to save lives.

G 7s another 500 million

UK, 100 million

Five million doses by the end of September

25 million more by the end of the year

Federal regulators

Johnson & Johnson vaccine by six weeks, up to 4.5 months

https://www.washingtonpost.com/health...

60 million doses to be discarded

South Africa implications

Chile

Population 19 million

https://www.washingtonpost.com/nation...

Santiago going into full lockdown from tomorrow

Fully vaccinated, 58%

At least one dose, 75%

Cases, + 7,700

Hospitals crowded

ICU at 98%

Jose Luis Espinoza, Chile’s National Federation of Nursing Associations

Members were on the verge of collapse

Chinese-made CoronaVac vaccine

20 million vaccine doses administered

15.8 million, CoronaVac vaccine

3.6 million Pfizer-BioNTech

A few Oxford-AstraZeneca

Health Ministry, Wednesday and Thursday, 27% of cases were in fully vaccinated

74% under the age of 49

April, University of Chile

CoronaVac, 56% effective two weeks after second dose

Pandemic fatigue, travel, variants

https://www.nature.com/articles/d4158...

The World Health Organization (1st June) approved CoronaVac at 51% effective at preventing COVID-19 (in late-stage trials)

https://papers.ssrn.com/sol3/papers.c...

HCWs in Brazil

100% effective at preventing severe disease and death

600 million doses have been delivered

(Sinopharm, efficacy of 79% against symptomatic disease)

PHE Delta viral assessment

https://assets.publishing.service.gov...