Does Vitamin D help with Immunity? | Vitamin D and Covid
Doctor Mike Hansen Doctor Mike Hansen
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 Published On May 31, 2020

Does Vitamin D help with Immunity? | Vitamin D and Covid

Hopefully, YT does not take this video down, as it's all based on medical studies. However, if they keep doing this, I will have to upload my videos to a different website.

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Vitamin D3 (Cholecalciferol) and Vitamin D2 (Ergocalciferol) and Calcitriol
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So what does not having enough vitamin D have to do with COVID? And IF insufficient vitamin D levels CAUSE more severe disease, why is that? Well, I have to first clarify that it's not proven that insufficient vitamin D levels lead to worse outcomes. But while it hasn’t been proven, it also certainly hasn’t been disproven. And there is more and more compelling evidence suggesting that lower levels lead to worse outcomes.

And there’s no question that vitamin D plays an important role in our immune system. More and more studies are coming out that are sorting out its exact role in this capacity. But the link between insufficient vitamin D status and the risk of certain infections remains cloudy. For example, in 2017, a meta-analysis study consisted of 25 separate randomized trials with about 11,000 patients in total, evaluating the incidence of acute respiratory disease.

Vitamin D supplementation reduced the percentage of patients experiencing an acute respiratory tract infection. The incidence of URTI in the vitamin D group was 40.3%, compared to 42.2% in the placebo group. In a subgroup analysis, vitamin D supplementation was most effective in patients with less than 10 ng/mL and those treated daily or weekly with smaller doses instead of a huge single dose.

The takeaway from this meta-analysis study is that being vitamin d deficient probably makes people more prone to getting upper respiratory infections and should take supplemental vitamin D. But people who have low levels should be taking supplemental vitamin D regardless. Vitamin D has major effects on nearly all our immune system cells, including dendritic cells, macrophages, and T and B lymphocytes. These immune cells have a receptor that binds to vitamin D, called the vitamin D receptor, or VDR.

Here are some questions we still need answers to:
1) what level of vitamin D is adequate to protect against or minimize the impact of COVID?
2) What level of vitamin D is considered too high
3) should more and more people get their vitamin D levels checked, especially during this pandemic, when fewer and fewer people are physically going to the doctor?
4) should people just supplement themselves? If so, how much?

These are all tough questions to answer, mainly because we won’t have RCT results for vitamin D anytime soon. However, given that low dose vitamin D is pretty darn safe, it seems quite reasonable for people to take a low dose supplement, especially if they think they might not be getting enough from sunlight or their diet. Of course, ideally, you want to have a discussion with your doctor if possible.

A common question is, How much Vitamin D should I take a day?
Personally, I take 1,000 IU per day. I know that I’m not going to run anywhere near toxic levels of vitamin D with that dose, while at the same time, I know that I won’t be vitamin D deficient.

Doctor Mike Hansen, MD
Internal Medicine | Pulmonary Disease | Critical Care Medicine
Website: https://doctormikehansen.com/
Doctor Hansen's Courses: https://doctormikehansen.com/courses/
Contact and Social Media Links: https://doctormikehansen.com/contact/

#covid #vitamind

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