This episode challenges common perceptions about exercise, delving deep into the benefits of vigorous exercise for not just physical health but also brain function, aging, and even cancer prevention. It tackles fundamental questions, like what genetic and metabolic adaptations occur with vigorous exercise and how it can contribute to combating heart's age-related changes. We also unpack how these rigorous exercises affect glucose transport, mitochondrial health, and brain health at an intricate level. Lastly, it introduces practical applications like the Norwegian 4x4 interval training protocol, the benefits of "exercise snacks," and how to incorporate vigorous-intensity exercise into everyday life.

Get the 9-page Cognitive Enhancement Blueprint:
https://bdnfprotocols.com/

Inside The Cognitive Enhancement Blueprint, you'll unearth:
• The optimal duration and intensity of workouts for cardiovascular health and cognition
• The duration and temperature of hot baths and sauna known to enhance biomarkers of brain health
• The proven benefits of high-intensity cycling for boosting brain function
• The omega-3 fatty acid dosage shown to increase biomarkers of improved cognition
• How polyphenols and flavonoids in your diet can amplify cognitive performance
• (and many more of Dr. Rhonda Patrick’s BDNF protocols)

CHAPTERS:
(00:00) Introduction
(01:51) What differentiates "vigorous" from "zone 2"
(02:23) Defining intensity with the talk test
(09:12) Why zone 2 training may not improve VO2 max
(11:34) Balancing zone 2 & vigorous-intensity workouts
(13:32) Norwegian 4x4 protocol improves VO2 max
(16:52) Methods to estimate VO2 max outside a lab
(19:49) What it takes to reverse 20 years of heart aging
(25:40) How HIIT reduces type 2 diabetes risk
(26:54) HIIT vs. Zone 2 for mitochondria
(29:25) Should committed exercisers practice 80/20 rule?
(32:35) Vigorous exercise enhances mitophagy
(35:20) Why lactate from HIIT benefits the brain
(37:45) How lactate allows "glucose sparing" in brain
(40:43) The BDNF benefits of HIIT
(41:59) Lactate signals the growth of new blood vessels
(44:15) Exercise intensity increases myokine release
(47:04) Exercise lowers mortality risk in cancer survivors
(48:13) Vigorous exercise kills circulating tumor cells
(49:53) Why exercise reduces depression and neurotoxicity (kynurenine mechanism)
(51:58) How "exercise snacks" reduce mortality

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#Exercise #Brain #BDNF