Leukocytes | White Blood Cells | Immune System

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Description:
There are two primary categories of WBCs; Granulocytes and Agranulocytes.

GRANULOCYTES: Neutrophils, Eosinophils & Basophils;
NEUTROPHILS: Polymorphonuclear neutrophil; Polymorphs.
EOSINOPHILS: Bilobed nucleus, granules stained by eosinophil/acidic dyes.
BASOPHILS: Bilobed nucleus, granules stained blue/basic/basophilic dyes.

AGRANULOCYTES: Monocytes & Macrophages.
MONOCYTES; granules are non-specific; kidney shaped nuclei.
LYMPHOCYTES; very large nucleus, very little cytoplasm.

TOTAL LEUKOCYTE COUNT (TLC):
Total no white cells in cubic mm of blood, 4000-11000/mm3.
Leukopenia, Leukocytosis defined.

DIFFERENTIAL LEUKOCYTE COUNT (DLC);
Neutrophils: 40%-75%; Neutropenia & Neutrophilia; acute inflammation; Pyogenic infection.
Eosinophils: 1%-6%; Eosinophilia; Parasitic infections & Allergic conditions.
Basophils: 0%-2%; Basophilia; Type 1 HS reactions.
Monocytes: 2%-10%; Monocytosis; Chronic infections; Tuberculous infections.

LYMPHOCYTES: 15-40%; Lymphocytosis; classically seen in viral infections & chronic infections.

ORIGIN:
Granulopoiesis.
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