Every year since 2005, a new season of Grey's Anatomy has been released. The series' fans have seen a lot over 18 seasons of Grey’s Anatomy. It would seem that nothing can surprise them, but the series continues to amaze, and the audience continues to shudder from the plot twists and turns, as the show will continue while Ellen Pompeo is filming Meredith Gray!

Also, over 18 seasons, viewers managed to meet and say goodbye to a lot of Fray’s Anatomy characters. And so we decided to look back at every unexpected Grey’s Anatomy cast exit and put together a list of the Grey’s Anatomy actors and characters that Grey's Anatomy fans miss the most.

So today OSSA is going to make a rate list of Grey’s Anatomy characters and cast members that fans miss most of all. The first who comes to mind, of course, is Mr. McDreamy. The love line between Meredith Gray and Derek Shepherd, also known as MerDer, made Patrick Dempsey a favorite of Grey's Anatomy fans. The fans were also sad to learn that their favorite Kate Walsh could be seen again in the image of Addison Montgommery only in the Grey’s Anatomy spin-off Private Practice.

It is also sad to remember that the departure of Catherine Heigl, who played the charming Izzy Stevens, was only due to her misunderstanding with the creator of Anatomy Gray, Shonda Rhimes. Also, fans miss Jesse Williams (Jackson Avery), Sarah Drew (April Kepner), Giacomo Gianniotti (Andrew de Luca), Sandra Oh (Cristina Yang), TR Knight (George O'Malley), Chyler Leigh (Lexie Gray), and of course Justin Chambers (Alex Karev). But who do Grey's Anatomy fans miss the most?

You will find out the answer to this question as soon as you watch our OSSA’m video about the most shocking actor's departure from the series Grey's Anatomy.
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