Vahan Kassabian, MD, Director of the Atlanta Prostate Center and Advanced Therapeutics at the Advanced Urology in Atlanta, Georgia, presents a case study to illustrate the benefits of treating certain prostate cancer patients using high-intensity focused ultrasound (HIFU) instead of radical prostatectomy and radiation therapy. He begins by reviewing the circumstances of the patient’s diseases in 2015, then summarizes treatment and followup from early 2016 through January 2021. Finally, he explains how HIFU has been beneficial for the patient so far and what options are available at this point in their still-evolving journey.