Among those with insomnia, Ambien remains the most popular sleeping pill approved by the FDA specifically for the purpose. Sleep disorders remain extremely frequent affecting between 6-10% of the population. Women suffer more sleep disturbances than men.

Previously restricted to fewer than 7-14 days due to a supposed lack of continuing effect, Ambien and similar hypnotics may now be prescribed for long term use. Special precautions are warranted for the elderly, those with liver disease and the debilitated.

Since Ambien acts to depress the central nervous system, extreme caution is warranted for those receiving other drugs that further deepen sedation. Among the dangerous pairings are Xanax, Valium, opioids, alcohol, trazodone, tramadol and certain antidepressants.

Women seem especially prone to lingering sleepiness or “clouded brain” during the day after taking Ambien. Even 8 hours after the pill, blood levels are still measurable in 15% of women but fewer than 3% of men. This prolonged effect creates potential danger with activities requiring mental alertness such as driving to work the next day. Extended release tablets further compound the problem.