1. A Fine Franzy - Almost Lover (Germany no.8, no other German top 40 hit)
2. Afroman - Because I Got High (USA no.13, no other US top 40 hit)
3. Alexander Rybak - Fairytale (UK no.10, no other UK top 40 hit)
4. Ana Johnsson - We Are (UK no.8, no other UK top 40 hit)
5. Andreas Johnson - Glorious (UK no.4, no other UK top 40 hit)
6. Cassie - Me & U (USA no.3, no other US top 40 hit)
7. The Click Five - Just the Girl (USA no.11, no other US top 40 hit)
8. Corinne Bailey Rae - Put Your Records On (UK no.2, no other UK top 30 hit)
9. Crazy Town - Butterfly (USA no.1, no other US top 40 hit)
10. Daniel Powter - Bad Day (US no.1, UK no.2, no other top 40 hit)
11. Dante Thomas - Miss California (feat. Pras) (Netherlands no.1, no other top 40 hit)
12. David Archuleta - Crush (USA no.2, no other US top 40 hit)
13. David Jordan - Sun Goes Down (UK no.4, no other UK top 40 hit)
14. Debelah Morgan - Dance with Me (US no.8, UK no.10, no other top 40 hit)
15. Dream - He Loves U Not (US no.2, no other top 30 hit)
16. Eamon - F**k It (I Don't Want You Back) (USA no.16, no other US top 40 hit)
17. Frankee - F.U.R.B. (F**k You Right Back) (UK no.1, no other UK top 40 hit)
18. Edward Maya & Vika Jigulina - Stereo Love (UK no.4, no other UK top 40 hit)
19. Elliott Yamin - Wait for You (USA no.13, no other US top 40 hit)
20. Emilíana Torrini - Jungle Drum (Germany no.1, no other German top 40 hit)
21. Estelle - American Boy (feat. Kanye West) (USA no.9, no other US top 40 hit)
22. Feist - 1234 (US & UK no.8, no other top 40 hit)
23. Fountains of Wayne - Stacy's Mom (US No.21, no other top 40 hit)
24. Gnarls Barkley - Crazy (US No.2, no other top 40 hit)
25. Haiducii - Dragostea din tei (Germany no.2, no other German top 40 hit)
26. Hellogoodbye - Here (In Your Arms) (UK No.4, USA No.14, no other top 40 hit)
27. Hoobastank - The Reason (US No.2, no other top 40 hit)
28. Howie Day - Collide (US No.20, no other top 40 hit)
29. Ian Carey Project - Get Shaky (UK no.9, no other UK top 40 hit)
30. J-Kwon - Tipsy (USA No.2, UK No.4, no other top 40 hit)
31. Jimmy Eat World - The Middle (US No.5, no other top 40 hit)
32. Kate Winslet - What If (UK no.6, no other UK top 40 hit)
33. Kevin Lyttle - Turn Me On (US No.4, no other top 40 hit)
34. Las Ketchup - The Ketchup Song (Aserejé) (UK no.1, no other UK top 40 hit)
35. Los Lonely Boys - Heaven (US No.16, no other top 40 hit)
36. Lumidee - Never Leave You (Uh Oooh, Uh Oooh) (US No.3, no other top 40 hit)
37. Mario Winans - I Don't Wanna Know (US No.2, no other top 40 hit)
38. Mary Mary - Shackles (Praise You) (UK no.5, no other UK top 30 hit)
39. Mattafix - Big City Life (Germany no.1, no other German top 30 hit)
40. Metro Station - Shake It (US No.10, UK no.6, no other top 40 hit)
41. Michael Andrews & Gary Jules - Mad World (UK no.1, no other UK top 40 hit)
42. Newton Faulkner - Dream Catch Me (UK no.7, no other UK top 40 hit)
43. Nina Sky (featuring Jabba) - Move Ya Body (US No.4, no other top 40 hit)
44. Nine Days - Absolutely (Story of a Girl) (US No.6, no other top 40 hit)
45. Paris Hilton - Stars Are Blind (US no.18 & UK no.5, no other UK top 40 hit)
46. Peter Bjorn and John - Young Folks (UK no.13, no other UK top 40 hit)
47. Phantom Planet - California (UK no.9, no other UK top 40 hit)
48. Sam Sparro - Black & Gold (UK no.2, no other UK top 40 hit)
49. Truth Hurts (feat. Rakim) - Addictive (US no.9 & UK no.3, no other top 40 hit)
50. Yael Naim - New Soul (US No.7, no other top 40 hit)