Cholsoon Jang, PhD is an Assistant Professor of Biological Chemistry at the University of California Irvine School of Medicine. Dr. Jang obtained bachelor’s and master’s degrees from Korea Advanced Institute of Science and Technology. He then received PhD from Harvard University and completed postdoctoral training at Princeton University. Dr. Jang’s laboratory focuses on understanding how dietary nutrients are processed in the body and exert health-beneficial or detrimental effects. Dr. Jang received prestigious awards such as Pinnacle Research Award from the American Association for the Study of Liver Disease and Edward Mallinckrodt Jr. Foundation Award, and several research grants from National Institute of Health. Dr. Jang has published 92 papers in prominent journals like Nature, Cell, and Science, which are cited over 8500 times. Dr. Jang is regularly invited to speak nationally and internationally on his research in nutrient metabolism.

In this episode we discuss:
- What’s the difference between fructose and glucose?
- The factors that affect your ability to metabolize fructose.
- The problems with current nutritional research.
- Should you be eating sugar?

Chapters:
00:00:00 - Introduction
00:04:28 - The Chemistry of Fructose and its Abundance in Processed Foods
00:08:42 - Solid vs Liquid Fructose
00:12:58 - Fructose Tolerance and Digestion
00:17:14 - Fructose Metabolism in the Intestine
00:21:08 - Fructose and Skeletal Muscle
00:25:21 - The Influence of Food on Our Bodies
00:29:21 - Organ Cross-Talk and Metabolism
00:33:28 - Brown Fat Thermogenesis
00:37:31 - Circadian Clocks and Glucose
00:41:39 - Rest and Eating Patterns
00:46:05 - Exercise and Metabolic Disorders
00:49:58 - The Effect of Fiber on Fructose Metabolism
00:54:05 - Challenges in Microbiome Research
00:58:12 - Metabolites in Different Organ Conditions
01:02:39 - The Importance of Kidney Metabolism

The Jang lab at UC Irvine: https://sites.uci.edu/janglab/

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