The fifteenth-generation Crown was unveiled as a concept at the 45th Tokyo Motor Show in October 2017 and went on sale on 26 June 2018.[88][89][90] The vehicle is built on a narrow version of the same TNGA-L platform that is used by other Lexus and luxury Toyota sedans.[91] Three engine choices are offered so as to provide buyers advantages in savings with regards to Japan's annual road tax obligation, and standard equipment content is increased with each trim package matched to the engine size.

Trim levels for the Japanese market Crown are B, S, G, G Executive, RS-B, RS, and RS Advance. All trim levels are offered with either rear wheel drive or full-time all-wheel drive. The S220 Crown carried over the 2.0-liter 8SR-FTS turbocharged four-cylinder gasoline engine from the previous model, introduced the 2.5 liter A25A-FXS paired with the Hybrid Synergy Drive system, as well as the 3.5-liter 8GR-FXS V6 paired with the Multi Stage Hybrid system from the Lexus LC 500h and LS 500h. The 2.0 L engine is only available in the rear wheel drive RS and RS Advance. All trim levels, except the rear wheel drive G Executive, can be purchased with the 2.5 L Hybrid. The 3.5 L Hybrid is only installed in the rear wheel drive RS Advance and G Executive. The only engine for the 4WD models is 2.5 L Hybrid. The 2.5 L Hybrid G Executive is the only version exported to Indonesia.[7]

In October 2019, the S220 Crown was selected by the government of Indonesia to serve as an official vehicle for cabinet ministers, replacing the older Crown Royal Saloon which had been in use since 2009.[7] However, unlike some preceding generations of the Crown in Indonesia, the S220 is imported in small numbers and unavailable for consumer purchase.

In 2020, a facelift of the S220 Crown was planned but rejected by president Akio Toyoda and scrapped in favour of developing a new generation.[92] However, in November 2020, the S220 received a minor update which brought a redesigned centre control stack and centre console to the interior, featuring a single 12.3-inch touchscreen and more intuitive physical climate controls in place of the previous dual-screen design.[93]

The fifteenth generation Crown is equipped with Toyota Safety Sense 2.0 just like most Toyota models for 2018.[96] Some added or improved features include:

(LTA) Lane Tracing Assist
Dynamic Radar Cruise Control (with all-speed vehicle following function)
(PCS) Pre-Collision System with Pedestrian Detection (can detect bicyclists and even pedestrians at night)
(AHB) Automatic High Beam
(RSA) Road Sign Assist
Advance car launch notification function