This animation demonstrates the behavior of a typical neuron at its resting membrane potential, and when it reaches an action potential and fires, transmitting an electrochemical signal along the axon. It shows how the various components work in concert: Dendrites, cell body, axon, sodium and potassium ions, voltage-gated ion channels, the sodium-potassium pump, and myelin sheaths. It also shows the stages of an action potential: Polarization, depolarization, and hyperpolarization.

The animation was co-developed by Harvard Extension School's Office of Digital Teaching and Learning, and instructors for the courses in neurobiology and human anatomy.

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