Boston Protein Design and Modeling Club
3.08K subscribers
46:39
Shedding light on functional dark matter with genomic language modeling
Boston Protein Design and Modeling Club
433 views • 9 days ago
58:58
Computational Design of non-porous, pH-responsive antibody nanoparticles
Boston Protein Design and Modeling Club
714 views • 1 month ago
1:26:30
Unsupervised early warning of viral antibody escape to design & test variant-proof therapeutics
Boston Protein Design and Modeling Club
522 views • 3 months ago
1:28:45
Bridging Biophysics and AI to Optimize Protein Design
Boston Protein Design and Modeling Club
1.5K views • 4 months ago
1:03:00
Learning transferable protein backmapping from conformational ensembles
Boston Protein Design and Modeling Club
537 views • 4 months ago
1:36:23
DiffDock: Diffusion Steps, Twists and Turns for Molecular Docking and Beyond!
Boston Protein Design and Modeling Club
1.4K views • 4 months ago
1:11:19
Computational design of autoinhibitory domains for a protease-activated PD-L1 antagonist
Boston Protein Design and Modeling Club
885 views • 5 months ago
1:05:57
Exploring structural heterogeneity through cryoEM, cryoET, and deep learning
Boston Protein Design and Modeling Club
429 views • 5 months ago
1:14:43
Investigating the volume &diversity of data needed for generalizable antibody-antigen ∆∆G prediction
Boston Protein Design and Modeling Club
1.2K views • 8 months ago
1:16:42
Exploration of novel functional sequence space using evolution-informed design
Boston Protein Design and Modeling Club
817 views • 9 months ago
59:18
Understanding & discovering fold-switching proteins by combining AlphaFold2 & sequence clustering
Boston Protein Design and Modeling Club
1.4K views • 9 months ago
1:19:48
Fragment-based backbone sampling & neural net derived potentials to design protein-binding peptides
Boston Protein Design and Modeling Club
814 views • 10 months ago
1:05:28
Building a global data supply chain to improve protein design and protect biodiversity
Boston Protein Design and Modeling Club
284 views • 10 months ago
1:17:45
Expanding the Universe of Functional Proteins by Computational Design
Boston Protein Design and Modeling Club
1.8K views • 1 year ago
1:30:36
Protein sequence design by explicit energy landscape optimization
Boston Protein Design and Modeling Club
1.3K views • 1 year ago
1:18:23
Designing ligand-binding proteins from scratch
Boston Protein Design and Modeling Club
2.2K views • 1 year ago
1:00:01
De novo design of mini-proteins to inhibit bacterial biofilm formation
Boston Protein Design and Modeling Club
1.3K views • 1 year ago
1:03:00
Tertiary motifs as building blocks for the design of protein binding peptides
Boston Protein Design and Modeling Club
571 views • 1 year ago
52:16
A computational approach to design structured peptides and predict peptide behavior in solution
Boston Protein Design and Modeling Club
770 views • 1 year ago
27:16
Designing cKIT Receptor Inhibitors to Clear Hematopoietic Stem Cells Prior to Bone Marrow Transplant
Boston Protein Design and Modeling Club
124 views • 1 year ago
1:17:30
Initial reaction to AlphaFold2 right after CASP14
Boston Protein Design and Modeling Club
867 views • 1 year ago
1:01:04
The 7 Habits of Highly Successful Protein Therapeutics
Boston Protein Design and Modeling Club
866 views • 1 year ago
1:02:51
Massively Parallel Protein Design to Develop Enzymes for Next-Generation Chemotherapy
Boston Protein Design and Modeling Club
355 views • 1 year ago
1:18:03
New tools for studying the mechanics of single proteins
Boston Protein Design and Modeling Club
296 views • 1 year ago
1:09:30
Why designs fail, and how they move
Boston Protein Design and Modeling Club
669 views • 1 year ago
1:10:06
De novo Glycan Modeling and Design
Boston Protein Design and Modeling Club
317 views • 1 year ago
43:15
A view of the structure-fitness landscape from an unsupervised vantage
Boston Protein Design and Modeling Club
383 views • 1 year ago
51:20
Rational de novo design of disulfide-rich miniprotein agonists and antagonists for family B GPCRs
Boston Protein Design and Modeling Club
603 views • 1 year ago
1:07:37
From large to small, protein design for stability and de novo interfaces
Boston Protein Design and Modeling Club
1.2K views • 1 year ago
1:18:46
Therapeutic enzyme engineering using a generative neural network
Boston Protein Design and Modeling Club
1.4K views • 2 years ago
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