SUCRALOSE damages DNA and may cause cancer and Leaky Gut

When a substance damages DNA, it is called genotoxic. Researchers have found that eating sucralose results in the body producing a substance called sucralose-6-acetate, which the new study now shows is genotoxic. The researchers also found sucralose-6-acetate in trace amounts in off-the-shelf products that are so high, they would exceed the safety levels currently allowed in Europe.

When the researchers exposed gut epithelial tissues, which line the gut wall, to these chemicals, they observed that both substances induced a "leaky gut." It means there is an increased permeability of the gut wall, where the chemicals damage the tight junctions that connect the cells in the gut lining.
The consequences of a leaky gut are concerning. Schiffman noted in a news release that it means that substances that should be eliminated through feces are instead leaking out of the gut and entering the bloodstream. Schiffman emphasizes, "This work raises a host of concerns about the potential health effects associated with sucralose and its metabolites."
Additionally, the researchers examined the genetic activity of the gut cells when exposed to sucralose-6-acetate. They discovered an increased activity in genes related to oxidative stress, inflammation, and carcinogenicity. These findings further contribute to the growing body of evidence indicating significant risks associated with sucralose.
Schiffman urges people to avoid products containing sucralose. He also notes that it is time to revisit the safety and regulatory status of sucralose. More so, she encourages people to avoid products containing sucralose as it is something you should not be eating.

https://www.medscape.com/viewarticle/...

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